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Effects of comprehensive therapy based on traditional Chinese medicine patterns on older patients with chronic obstructive pulmonary disease: a subgroup analysis from a four-center, randomized, controlled study

null

《医学前沿(英文)》 2014年 第8卷 第3期   页码 368-375 doi: 10.1007/s11684-014-0360-0

摘要:

This study aimed to evaluate the efficacy of comprehensive therapy based on traditional Chinese medicine (TCM) patterns on older patients with chronic obstructive pulmonary disease (COPD) through a four-center, open-label, randomized controlled trial. Patients were divided into the trial group treated using conventional western medicine and Bu-Fei Jian-Pi granules, Bu-Fei Yi-Shen granules, and Yi-Qi Zi-Shen granules based on TCM patterns respectively; and the control group treated using conventional western medicine. A total of 136 patients≥65 years completed the study, with 63 patients comprising the trial group and 73 comprising the control group. After the six-month treatment and the 12-month follow-up period, significant differences were observed between the trial and control groups in the following aspects: frequency of acute exacerbation (P≤0.040), duration of acute exacerbation (P = 0.034), symptoms (P≤0.034), 6-min walking distance (6MWD) (P≤0.039), dyspnea scale (P≤0.036); physical domain (P≤0.019), psychological domain (P≤0.033), social domain (P≤0.020), and environmental domain (P≤0.044) of the WHOQOL-BREF questionnaire; and daily living ability domain (P≤0.007), social activity domain (P≤0.018), depression symptoms domain (P≤0.025), and anxiety symptoms domain (P≤0.037) of the COPD-QOL. No differences were observed between the trial and control groups with regard to FVC, FEV1, and FEV1%.

关键词: chronic obstructive pulmonary disease     older adult     clinical trial     Bu-Fei Jian-Pi granules     Bu-Fei Yi-Shen granules     Yi-Qi Zi-Shen granules    

Approaching the binding between Cu(II) and aerobic granules by a modified titration and µ-XRF

Hongwei LUO,Longfei WANG,Zhonghua TONG,Hanqing YU,Guoping SHENG

《环境科学与工程前沿(英文)》 2016年 第10卷 第2期   页码 362-367 doi: 10.1007/s11783-015-0803-0

摘要: Interactions between metals and activated sludge can substantially affect the fate and transport of heavy metals in wastewater treatment plants. Therefore, it is important to develop a simple, fast and efficient method to elucidate the interaction. In this study, a modified titration method with a dynamic mode was developed to investigate the binding of Cu(II), a typical heavy metal, onto aerobic granules. The titration results indicated that pH and ionic strength both had a positive effect on the biosorption capacity of the granular sludge. The -XRF results demonstrated that the distribution of metals on the granular surface was heterogeneous, and Cu showed strong correlations and had the same “hot spots” positions with other metal ions (e.g., Ca, Mg, Fe etc.). Ion exchange and complexing were the main mechanisms for the biosorption of Cu(II) by aerobic granules. These results would be beneficial for better understanding of Cu(II) migration and its fate in wastewater treatment plants.

关键词: aerobic granules     Cu(II)     modified titration     µ-XRF analysis    

Measurement of activity coefficients at infinite dilution for hydrocarbons in imidazolium-based ionic liquids and QSPR model

ZHU Jiqin, YU Yanmei, CHEN Jian, FEI Weiyang

《化学科学与工程前沿(英文)》 2007年 第1卷 第2期   页码 190-194 doi: 10.1007/s11705-007-0035-3

摘要: The separations of olefin/paraffin, aromatic/aliphatic hydrocarbons or olefin isomers using ionic liquids instead of volatile solvents have interested many researchers. Activity coefficients γ at infinite dilution of a solute in ionic liquid are generally used in the selection of solvents for extraction or extractive distillation. In fact, the measurement of γ by gas-liquid chromatography is a speedy and cost-saving method. Activity coefficients at infinite dilution of hydrocarbon solutes, such as alkanes, hexenes, alkylbenzenes, styrene, in 1-allyl-3-methylimidazolium tetrafluoroborate ([AMIM][BF]) and 1-butyl-3-methyl imidazolium hexafluorophosphate ([BMIM][PF6]), 1-isobutenyl-3-methylimidazolium tetrafluoroborate ([MPMIM][BF]) and [MPMIM][BF]-AgBF have been determined by gas-liquid chromatography using ionic liquids as stationary phase. The measurements were carried out at different temperatures from 298 to 318 K. The separating effects of these ionic liquids for alkanes/hexane, aliphatic hydrocarbons/benzene and hexene isomers have been discussed. The hydrophobic parameter, dipole element, frontier molecular orbital energy gap and hydration energy of these hydrocarbons were calculated with the PM3 semi-empirical quantum chemistry method. The quantitative relations among the computed structure parameters and activity coefficients at infinite dilution were also developed. The experimental activity coefficient data are consistent with the correlated and predicted results using QSPR models.

关键词: cost-saving     consistent     coefficient     measurement     separating    

Nitrifying and denitrifying bacteria in aerobic granules formed in sequencing batch airlift reactors

WANG Fang, YANG Fenglin, QI Aijiu

《环境科学与工程前沿(英文)》 2007年 第1卷 第2期   页码 184-189 doi: 10.1007/s11783-007-0032-2

摘要: The purpose of this study was to investigate nitrifying bacteria and denitrifying bacteria isolated from aerobic granules. Aerobic granules were formed in an internal-circulate sequencing batch airlift reactor (SBAR) and biodegradation of NH3--N was analyzed in the reactor. Bacteria were isolated and determined from aerobic granules using selected media. The growth properties and morphology of bacteria colonies were observed by controlling aerobic or anaerobic conditions in the culture medium. It was found that bacteria in aerobic granules were diverse and some of them were facultative aerobes. The diversity of bacteria in aerobic granules was a premise of simultaneous nitrification and denitrification.

Treatment of swine wastewater in aerobic granular reactors: comparison of different seed granules as

Lin LIU,Qiyu YOU,Valerie GIBSON,Xu HUANG,Shaohua CHEN,Zhilong YE,Chaoxiang LIU

《环境科学与工程前沿(英文)》 2015年 第9卷 第6期   页码 1139-1148 doi: 10.1007/s11783-015-0823-9

摘要: The granulation process, physic-chemical properties, pollution removal ability and bacterial communities of aerobic granules with different feed-wastewater (synthetic wastewater, R1; swine wastewater, R2), and the change trend of some parameters of two types of granules in long-term operated reactors treating swine wastewater were investigated in this experiment. The result indicated that aerobic granulation with the synthetic wastewater had a faster rate compared with swine wastewater and that full granulation in R1 and R2 was reached on the 30th day and 39th day, respectively. However, although the feed wastewater also had an obvious effect on the biomass fraction and extracellular polymeric substances of the aerobic granules during the granulation process, these properties remained at a similar level after long-term operation. Moreover, a similar increasing trend could also be observed in terms of the nitrogen removal efficiencies of the aerobic granules in both reactors, and the average specific removal rates of the organics and ammonia nitrogen at the steady-state stage were 35.33 mg·g VSS and 51.46 mg·g VSS for R1, and 35.47 mg·g VSS and 51.72 mg·g VSS for R2, respectively. In addition, a shift in the bacterial diversity occurred in the granulation process, whereas bacterial communities in the aerobic granular reactor were not affected by the seed granules after long-term operation.

关键词: aerobic granules     livestock wastewater     sequencing batch reactor     biological wastewater treatment     bacterial community    

4Pi荧光超分辨显微术综述 Review

郝翔, 李依明, 傅爽, 李旸晖, 许迎科, 匡翠方, 刘旭

《工程(英文)》 2022年 第11卷 第4期   页码 146-153 doi: 10.1016/j.eng.2020.07.028

摘要: 回顾这些历程,一个重要的里程碑是基于两个对置物镜的4Pi 显微架构及其超分辨版本的出现。鉴于此,本文综述了4Pi 超分辨显微术的近期进展。总体上,4Pi 超分辨显微镜为透明样品观测提供了一
种能够突破衍射极限、非侵入、各向同性的三维分辨率的技术手段。具体而言,本文针对目标开关和随机开关两个主要4Pi 超分辨显微术版本,讨论了它们的架构、原理、应用和未来发展趋势。

关键词: 荧光超分辨显微术     超分辨成像     4Pi超分辨显微术     isoSTED     4Pi-SMLM    

Ecological assessment of lakeshore wetland rehabilitation on eastern route of South-to-North Water Transfer Project

ZHANG Jian, Lu Yifeng, JING Yuming, ZHANG Bo, ZHANG Chenglu, MENG Fei, ZHANG Huayong

《环境科学与工程前沿(英文)》 2008年 第2卷 第3期   页码 306-310 doi: 10.1007/s11783-008-0057-1

摘要: To evaluate the ecological effects of lakeshore wetland rehabilitation on the eastern route of the South-to-North Water Transfer Project, species composition, coverage, height, and biomass of wetland communities at 22 sites of the study area on the shore of Nansi Lake in April and May 2007 were investigated. The wetlands under investigation were divided into platform fields, transition zones, and shallow water zones according to differences in elevations, water levels, and human activities. The species richness index, Shannon-Wiener index, Simpson index, and Pielou Evenness index were adopted to delineate and discuss the ecological effects of lakeshore wetland rehabilitation in 22 quadrates. Results showed that the species richness of the wetland areas after 2 years’ rehabilitation amounted to 47 of 24 families, higher than 25 of 20 families in areas without rehabilitation. The biodiversity index and abundance index of rehabilitated areas were also higher than those of platform fields and fish ponds where there was no rehabilitation. In addition, the Shannon-Wiener index, Simpson index, and community evenness index of platform fields in rehabilitated wetland areas were 1.619, 0.745, and 0.860, respectively, higher than those of the platform fields before rehabilitating. The results suggested that the constructed lakeshore wetland played an important role in protecting the diversity of species.

关键词: community     South-to-North     Shannon-Wiener     Evenness     addition    

基于半导体纳米晶体的神经突触器件 Review

步明轩1,2,王越1,2,尹蕾1,2,童周禹1,2,张懿强3,杨德仁1,2,4,5,皮孝东1,2,4,5

《信息与电子工程前沿(英文)》 2022年 第23卷 第11期   页码 1579-1601 doi: 10.1631/FITEE.2100551

摘要:

近年来,人们对信息处理的需求日益增长,脑启发式神经形态器件得到了广泛的关注。突触器件作为一类重要的神经形态器件,在短短几年内迅速升温。在用于制备突触器件的各种材料中,半导体纳米晶体(NCs)因其优异的电学和光学性能而成为首选材料之一。本综述论文首先介绍了基于半导体纳米晶体的突触器件的研究背景及半导体纳米晶体的基本性质。然后,根据器件有源层所用纳米晶体种类的不同,分类介绍了基于纳米晶体的突触器件的最新研究进展。最后,讨论了基于半导体纳米晶体的突触器件目前仍面临的问题和挑战。

关键词: 半导体纳米晶体;突触器件;神经形态计算    

Heat and mass transfer of ammonia-water in falling film evaporator

Xianbiao BU, Weibin MA, Huashan LI

《能源前沿(英文)》 2011年 第5卷 第4期   页码 358-366 doi: 10.1007/s11708-011-0161-y

摘要: To investigate the performance of heat and mass transfer of ammonia-water during the process of falling film evaporation in vertical tube evaporator, a mathematical model of evaporation process was presented, the solution of which that needed a coordinate transformation was based on stream function. The computational results from the mathematical model were validated with experimental data. Subsequently, a series of parameters, such as velocity, film thickness and concentration, etc., were obtained from the mathematical model. Calculated results show that the average velocity and the film thickness change dramatically at the entrance region when <100 mm, while they vary slightly with the tube length in the fully developed region when >100 mm. The average concentration of the solution reduces along the tube length because of evaporation, but the reducing tendency becomes slow. It can be concluded that there is an optimalβrelationship between the tube length and the electricity generated. The reason for the bigger concentration gradient in the direction is that the smooth tube is chosen in the calculation. It is suggested that the roll-worked enhanced tube or other enhanced tube can reduce the concentration gradient in the film thickness direction and enhance the heat and mass transfer rate.

关键词: falling film evaporation     ammonia-water     heat and mass transfer    

时序增强的知识记忆网络在问答中的应用 Article

Xin-yu DUAN, Si-liang TANG, Sheng-yu ZHANG, Yin ZHANG, Zhou ZHAO, Jian-ru XUE, Yue-ting ZHUANG, Fei WU

《信息与电子工程前沿(英文)》 2018年 第19卷 第1期   页码 104-115 doi: 10.1631/FITEE.1700788

摘要: 问答系统旨在为人类以自然语言提出的问题提供具体答案。如何对问题做出有效回答是该领域的热点问题。在问答系统研究中,对于给定问题与其相应答案,现有方法通常侧重于模拟问答语料间语义相关性或句法关系。当一个问题包含的答案线索非常少时,这些模型大多受到影响。本文设计了一个名为时序增强型知识记忆网络(temporality-enhanced knowledge memory network, TE-KMN)的架构,并将该模型应用于一个名为Quiz Bowl的知识竞赛问答数据集。与多数现有方法不同,该模型不仅对文本内容进行编码,也对问题中连续语句间能够逐步揭示答案的时序线索进行编码。此外,该模型通过协同使用外部知识,能够更好理解给定问题。实验结果表明,该方法性能优于目前几种最先进方法。

关键词: 问答系统;知识记忆;时序增强    

RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway

《医学前沿(英文)》 2023年 第17卷 第1期   页码 143-155 doi: 10.1007/s11684-022-0929-y

摘要: Gliomas are the most common central nervous system tumours; they are highly aggressive and have a poor prognosis. RGS16 belongs to the regulator of G-protein signalling (RGS) protein family, which plays an important role in promoting various cancers, such as breast cancer, pancreatic cancer, and colorectal cancer. Moreover, previous studies confirmed that let-7c-5p, a well-known microRNA, can act as a tumour suppressor to regulate the progression of various tumours by inhibiting the expression of its target genes. However, whether RGS16 can promote the progression of glioma and whether it is regulated by miR let-7c-5p are still unknown. Here, we confirmed that RGS16 is upregulated in glioma tissues and that high expression of RGS16 is associated with poor survival. Ectopic deletion of RGS16 significantly suppressed glioma cell proliferation and migration both in vitro and in vivo. Moreover, RGS16 was validated as a direct target gene of miR let-7c-5p. The overexpression of miR let-7c-5p obviously downregulated the expression of RGS16, and knocking down miR let-7c-5p had the opposite effect. Thus, we suggest that the suppression of RGS16 by miR let-7c-5p can promote glioma progression and may serve as a potential prognostic biomarker and therapeutic target in glioma.

关键词: RGS16     let-7c-5p     glioma     proliferation     migration    

Composite adsorbents of CaCl

Huashan LI, Xianbiao BU, Lingbao WANG, Zhenneng LU, Weibin MA

《能源前沿(英文)》 2012年 第6卷 第4期   页码 356-360 doi: 10.1007/s11708-012-0207-9

摘要: Composite adsorbents of CaCl and sawdust prepared by carbonization for adsorption refrigeration with NH as refrigerant are tested, and the effects of carbonization temperature on the sorption capacity and rate are analyzed. The results show that the amount of pores in the sawdust of the composite adsorbents carbonized, apart from the content of CaCl , is the most dominant factor influencing the NH sorption on composite adsorbents. The optimum carbonization temperature is 700°C, which gives the maximal NH sorption capacity as high as 0.774 kg of NH per kg of the composite, and the specific cooling power is approximately between 338 and 869 W/kg with the cycle duration varying from 5 to 20 minutes. The present study demonstrates that the composite absorbent of CaCl and sawdust prepared by carbonization is more promising and competitive for adsorption refrigeration application.

关键词: adsorption refrigeration     composite adsorbent     calcium chloride     sawdust     carbonization    

Identification and ranking of the risky organic contaminants in the source water of the Danjiangkou reservoir

Qingwei BU, Donghong WANG, Zijian WANG, Junnong GU

《环境科学与工程前沿(英文)》 2014年 第8卷 第1期   页码 42-53 doi: 10.1007/s11783-013-0499-y

摘要: The Danjiangkou reservoir was selected to provide the source water for the middle routes of the South to North Water Transfer Project, which has provoked many environmental concerns. To date, investigations of water contamination of the source water of the Danjiangkou reservoir with organic micro-pollutants have been limited. This study was conducted to identify and rank organic contaminants that pose risks in the Danjiangkou reservoir. To this end, the Chemical Hazard Evaluation and Management Strategies (CHEMS-1) approach was adapted to integrate the deconvolution technology of qualitative identifying contaminants for site-specific environmental matrices. The samples were screened for the presence of 1093 contaminants using deconvolution technologies and the hazard values of the identified contaminants were calculated using the adapted CHEMS-1 approach according to their hazardous properties and occurrence in source water. The results showed that 46 contaminants from 1093 targets were present in Danjiangkou water, 23 of which appeared at frequencies higher than 50%, and 15 of which were identified as priorities. Over half (53%) of the high-ranked contaminants were polycyclic aromatic hydrocarbons (PAHs), with chrysene ranked highest on the list. Health risk assessment of the top-ranked PAHs was conducted and revealed that cancer risks of PAHs detected in the source water of Danjiangkou to different populations ranged from 10 to 10 , indicating a low cancer risk to consumers. The results of this study indicated that the adapted CHEMS-1 approach was feasible for site-specific screening of organic contaminants to identify and rank potential priority pollutants.

关键词: identification and ranking     source water     deconvolution     risk assessment     Danjiangkou     South to North Water Transfer Project    

新型硅基光纤研究进展 Special Feature on Optoelectronic Devices and Inte

Ting-yun WANG, Fu-fei PANG, Su-juan HUANG, Jian-xiang WEN, Huan-huan LIU, Li-bo YUAN

《信息与电子工程前沿(英文)》 2019年 第20卷 第4期   页码 481-489 doi: 10.1631/FITEE.1900017

摘要: 综述了两类新型光纤的最新研究进展,主要包括掺铋、铝、铈等元素的二氧化硅光纤和微结构多芯光纤。作为掺杂特殊元素的光纤,铋铝共掺杂二氧化硅光纤的荧光光谱波长为1000到1400 nm,半高宽(FWHM)约为150 nm,可用于光纤放大器和激光系统。铈掺杂光纤的激发和发射中心波长分别约为340和430 nm。在纤芯中掺杂高浓度氧化铝的蓝宝石衍生光纤(SDF)经电弧放电加热、冷却处理后可形成莫来石。SDF可进一步开发为能承受1200 °C高温的法布里—珀罗干涉仪,用于高温传感。由于强消逝场,微结构多芯光纤被广泛应用于生物光纤传感、化学测量等领域。同轴芯光纤是一种具有两个同轴双波导纤芯的新型光纤。将光纤端制备成锥状,能产生紧致聚焦光场,可应用于光学捕获和微粒操纵。本文讨论了这些新型光纤的研究进展。

关键词: 光纤;光纤器件;基于二氧化硅特种光纤    

A sampling method based on URL clustering for fast web accessibility evaluation

Meng-ni ZHANG,Can WANG,Jia-jun BU,Zhi YU,Yu ZHOU,Chun CHEN

《信息与电子工程前沿(英文)》 2015年 第16卷 第6期   页码 449-456 doi: 10.1631/FITEE.1400377

摘要: When evaluating the accessibility of a large website, we rely on sampling methods to reduce the cost of evaluation. This may lead to a biased evaluation when the distribution of checkpoint violations in a website is skewed and the selected samples do not provide a good representation of the entire website. To improve sampling quality, stratified sampling methods first cluster web pages in a site and then draw samples from each cluster. In existing stratified sampling methods, however, all the pages in a website need to be analyzed for clustering, causing huge I/O and computation costs. To address this issue, we propose a novel page sampling method based on URL clustering for web accessibility evaluation, namely URLSamp. Using only the URL information for stratified page sampling, URLSamp can efficiently scale to large websites. Meanwhile, by exploiting similarities in URL patterns, URLSamp cluster pages by their generating scripts and can thus effectively detect accessibility problems from web page templates. We use a data set of 45 web sites to validate our method. Experimental results show that our URLSamp method is both effective and efficient for web accessibility evaluation.

关键词: Page sampling     URL clustering     Web accessibility evaluation    

标题 作者 时间 类型 操作

Effects of comprehensive therapy based on traditional Chinese medicine patterns on older patients with chronic obstructive pulmonary disease: a subgroup analysis from a four-center, randomized, controlled study

null

期刊论文

Approaching the binding between Cu(II) and aerobic granules by a modified titration and µ-XRF

Hongwei LUO,Longfei WANG,Zhonghua TONG,Hanqing YU,Guoping SHENG

期刊论文

Measurement of activity coefficients at infinite dilution for hydrocarbons in imidazolium-based ionic liquids and QSPR model

ZHU Jiqin, YU Yanmei, CHEN Jian, FEI Weiyang

期刊论文

Nitrifying and denitrifying bacteria in aerobic granules formed in sequencing batch airlift reactors

WANG Fang, YANG Fenglin, QI Aijiu

期刊论文

Treatment of swine wastewater in aerobic granular reactors: comparison of different seed granules as

Lin LIU,Qiyu YOU,Valerie GIBSON,Xu HUANG,Shaohua CHEN,Zhilong YE,Chaoxiang LIU

期刊论文

4Pi荧光超分辨显微术综述

郝翔, 李依明, 傅爽, 李旸晖, 许迎科, 匡翠方, 刘旭

期刊论文

Ecological assessment of lakeshore wetland rehabilitation on eastern route of South-to-North Water Transfer Project

ZHANG Jian, Lu Yifeng, JING Yuming, ZHANG Bo, ZHANG Chenglu, MENG Fei, ZHANG Huayong

期刊论文

基于半导体纳米晶体的神经突触器件

步明轩1,2,王越1,2,尹蕾1,2,童周禹1,2,张懿强3,杨德仁1,2,4,5,皮孝东1,2,4,5

期刊论文

Heat and mass transfer of ammonia-water in falling film evaporator

Xianbiao BU, Weibin MA, Huashan LI

期刊论文

时序增强的知识记忆网络在问答中的应用

Xin-yu DUAN, Si-liang TANG, Sheng-yu ZHANG, Yin ZHANG, Zhou ZHAO, Jian-ru XUE, Yue-ting ZHUANG, Fei WU

期刊论文

RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway

期刊论文

Composite adsorbents of CaCl

Huashan LI, Xianbiao BU, Lingbao WANG, Zhenneng LU, Weibin MA

期刊论文

Identification and ranking of the risky organic contaminants in the source water of the Danjiangkou reservoir

Qingwei BU, Donghong WANG, Zijian WANG, Junnong GU

期刊论文

新型硅基光纤研究进展

Ting-yun WANG, Fu-fei PANG, Su-juan HUANG, Jian-xiang WEN, Huan-huan LIU, Li-bo YUAN

期刊论文

A sampling method based on URL clustering for fast web accessibility evaluation

Meng-ni ZHANG,Can WANG,Jia-jun BU,Zhi YU,Yu ZHOU,Chun CHEN

期刊论文